vitamin c and vitamin e protected b95-8 and balb/c-3t3 cells from apoptosis induced by intermittent 50hz elf-emf radiation

نویسندگان

zhen ding

jintao li

fan li

mohammadreza mohammadzad mephryar

چکیده

background: the extremely low-frequency electromagnetic field (elf-emf), mainly emitted by electric transmission lines and household electronic appliances, is becoming a worldwide health risk. it is imperative to investigate the biological impacts of elf-emf and to identify products that are resistant to the radiation from 50 hz elf-emf. in this study, we investigated the biological impacts of apoptosis caused by 50 hz power line elf-emf and the protective effects of vit c and vit e. methods: we conducted this study in beijing, china in 2013. b 95-8  and balb/c-3t3 cells were divided into a sham group, an expo group and 3 expo groups in which the cells were preincubated with various concentrations of vit c and vit e. then, all of the cells were exposed to 50 hz power line elf-emf and examined for apoptosis. the cells were collected for apoptosis detection after exposure. results: the percent of cells that undergoing apoptosis and preincubated with various concentrations of vit c and vit e were significantly lower than in the expo group. conclusion: vit c and vit e exert significant protective effects from 50 hz elf-emf radiation. the optimal protective concentrations of vit c and vit e are 10 μmol/l and 25 μmol/l, respectively. the protective effect of vitamins was more apparent for balb/c-3t3 cells than b 95-8 cells.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Vitamin C and Vitamin E Protected B95-8 and Balb/c-3T3 Cells from Apoptosis Induced by Intermittent 50Hz ELF-EMF Radiation

BACKGROUND The extremely low-frequency electromagnetic field (ELF-EMF), mainly emitted by electric transmission lines and household electronic appliances, is becoming a worldwide health risk. It is imperative to investigate the biological impacts of ELF-EMF and to identify products that are resistant to the radiation from 50 Hz ELF-EMF. In this study, we investigated the biological impacts of a...

متن کامل

Oral Administration of Vitamin C, Cimetidine and Famotidine on Micronuclei Induced by Low Dose Radiation in Mouse Bone Marrow Cells

 Background: In many studies, chemicals and natural materials were tested to reduce the harmful effects of radiation. It is known that Famotidine and vitamin C reduce DNA damage.Objective: The aim of this study was to evaluate the radioprotective effect of vitamin C, Cimetidine and Famotidine on gamma-radiation-induced damage on mouse bone marrow. Methods: Six-to-seven week male NMRI mice (28...

متن کامل

Protective effects of omega-3, atorvastatin, vitamin E and vitamin C against doxorubicin-induced cardiotoxicity in rats: a comparison study

Introduction: The stress-oxidative is involved in doxorubicin (DOX)-induced cardiotoxicity. Due to the potential and previous reported for antioxidant properties of atorvastatin, omega-3, vitamin E and vitamin C, their efficacy to prevention of DOX-induced cardiotoxicity was investigated in this study. Methods: Fifty-six male rats were divided into 8 groups which received omega-3, atorvastati...

متن کامل

Protective effects of famotidine and vitamin C against radiation induced cellular damage in mouse spermatogenesis process

Background: Radioprotective effect of famotidine was previously shown on radiation induced micronuclei and chromosomal aberrations in human peripheral lymphocytes and mouse bone marrow cells however, its radioprotective property has never been studied in mouse spermatogenesis. It was also shown that vitamin C as an antioxidant also exert its radioprotective effect on many biological s...

متن کامل

Study Of Interaction of Glutathione, Vitamin C and Vitamin E Under Hyperbaric Oxygen

In order to study the interaction of glutathione, vitamin C and vitamin E under hyperoxia (95 % oxygen) and hyperbaric oxygen (2.5 atmospheric pressure), 20 days old male Guinea pigs were fed with basal vitamin C free diet, while receiving a vitamin C supplement of either high concentration (50 mg/day) or low concentration (1 mg/day) for two weeks. Animals were than exposed to hyperoxia and hyp...

متن کامل

Consumption of antioxidant dietary agents, curcumin and vitamin C, protects cellular DNA from gamma-radiation

Background: Exposure to ionizing radiation results in genotoxicity and the unrepaired lesions in cellular DNA results in cell cycle arrest, reproductive death, interphase death, division delay, chromosome aberrations, mutations, etc. leading to the intensive destruction of cells and violation of their proliferative capacity there by adversely affecting the mammalian system. Since ionizing radia...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
iranian journal of public health

جلد ۴۶، شماره ۱، صفحات ۲۳-۳۴

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023